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(+49)231 755-2339

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(+49)231 755-2341

Room G2-R3.20

Curriculum Vitae

Field of Research

To obtain and increase the amount of consistent in-spec crystalline products, the control of their quality towards, e.g., a specific crystal size distribution (CSD), purity or morphology is essential particularly for the pharmaceutical and specialty chemical industry. Until now, in the sector mentioned above batch crystallization is favored despite many processes prior to crystallization are performed in a continuous mode. Thus, the need for continuous crystallization in mesoscale apparatuses is of major interest.

Thereby, the slug flow crystallizer (SFC) is a promising apparatus to obtain an enhanced product quality by e.g., narrowing the CSD. The segmented flow made up of liquid and gaseous compartments shows a well-mixed behavior inside the liquid slugs without introducing the influence of an external mixer into the system. The focus is set on the development and characterization of an SFC such that a controlled crystalline product quality is reached. These studies are compared to a commercially available continuous crystallizer to find the best performing crystallizer with regard to the respective crystalline product quality desired.

Publications

Papers

•  Maren Termühlen; Benedikt Strakeljahn; Gerhard Schembecker; Kerstin Wohlgemuth
  Quantification and Evaluation of Operating Parameters’ Effect on Suspension Behavior for Slug Flow Crystallization
  Chemical Engineering Science 243 (2021) 116771
  

• Maren Termühlen, Matthias Markus Etmanski, Ines Kryschewski, Anne Cathrine Kufner, Gerhard Schembecker, Kerstin Wohlgemuth
  Continuous Slug Flow Crystallization: Impact of Design and Operating Parameters on Product Quality
  Chemical Engineering Research and Design ( https://doi.org/10.1016/j.cherd.2021.04.006 )

• Maren Termühlen, Benedikt Strakeljahn, Gerhard Schembecker, Kerstin Wohlgemuth
  Characterization of slug formation towards the performance of air-liquid segmented flow
  Chemical Engineering Science, 207 (2019) 1288-1298

• Marie-Christine Lührmann, Maren Termühlen, Jan Timmermann, Gerhard Schembecker, Kerstin Wohlgemuth
  Induced nucleation by gassing and its monitoring for the design and operation of an MSMPR cascade
  Chemical Engineering Science, 192 (2018) 840-849

• Marie-Christine Ostermann, Maren Termühlen, Gerhard Schembecker, Kerstin Wohlgemuth
  Growth Rate Measurements of Organic Crystals in a Cone-Shaped Fluidized-Bed Cell
  Chemical Engineering and Technology 41 (2018) 1165-1172
  
  

Oral Presentations

• M. Termühlen, A. C. Kufner, M. Etmanski, G. Schembecker, K. Wohlgemuth
  Continuous Slug Flow Crystallization Focusing on Enhanced Product Quality Control
  Online Präsentation Jahrestreffen der ProcessNet-Fachgruppe Kristallisation (2020)

• M. Termühlen, M. Etmanski, I. Kryschewski, G. Schembecker, K. Wohlgemuth
  Operating Window and Cooling Concept for Continuous Slug Flow Crystallization
  Jahrestreffen der ProcessNet-Fachgruppe Kristallisation, Bamberg (2019)

• M. Termühlen, B. Strakeljahn, I. Kryschewski, G. Schembecker, K. Wohlgemuth
  Characterization of Flow Regime and Solid Suspension Behavior for the Design of a Continuous Slug Flow Crystallizer
  25th International Workshop on Industrial Crystallization “BIWIC”, Rouen, FRA (2018)

• M. Termühlen, B.Strakeljahn, G.Schembecker, K.Wohlgemuth
  Characterization of Flow Regime and Solid Suspension within Continuous Slug Flow Crystallization
  Jahrestreffen der ProcessNet-Fachgruppe Kristallisation, Bremen (2018)