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Claas Steenweg

Claas Steenweg Photo of Claas Steenweg

Telephone
(+49)231 755-2339

Fax
(+49)231 755-2341

Address

Laboratory of Plant and Process Design
Emil-Figge-Str. 70
Geschossbau 2
44227 Dortmund
Deutschland

Room G2-R3.14

Contents

Curriculum Vitae

Born May 31st, 1993 in Dortmund (Germany
2003 – 2012 Max-Planck-Gymnasium, Dortmund (Germany)
2012 – 2016

B.Sc. Chemical Engineering Studies, TU Dortmund University

Bachelor thesis: Investigating the Reuse of Engineering in Module-based Plant Design on P&ID Level

2014 Semester abroad at Hong Kong University of Science and Technology (HKUST)
2016 – 2018

M.Sc. Chemical Engineering Studies, TU Dortmund University

Master thesis: Experimental and Theoretical Investigations for the Model Discrimination of Distillation Processes in Packed Columns

Since 2018

PhD at the Laboratory of Plant and Process Design, TU Dortmund University

Field of Research: Continuous crystallization, Continuous solid-liquid separation

Field of research

For the paradigm shift from batch to continuous operation in pharmaceutical industry, innovative process solutions are required to extend unit operations that have historically been batch operations, such as crystallization. Different concepts for continuous crystallization are present to improve the product qualities such as crystal size, shape, and purity. However, crystallization needs additional downstream processes as filtration, washing and drying to obtain the final product.

 

These continuous isolation techniques are relatively rare in the pharmaceutical industry and specialty chemical industry, because of relatively low production capacities. The lack of commercial laboratory and manufacturing continuous filtration units leads to a significant gap in the development of full continuous manufacturing processes. Thus, a continuous small-scale solid/liquid filtration device will be developed and characterized. Subsequently, the device will be connected to different continuous crystallizers to enable a full continuous process.
Funding: This research work is funded by the state of North-Rhine Westphalia (NRW) and the European Regional Development Fund (EFRE), Project “NRW Patent Validation Program” (Grant EFRE-0400357).

EU_InvestitionEFRE

Publications

Papers

  • Claas Steenweg, Jonas Habicht, Kerstin Wohlgemuth
    Continuous Isolation of Particles with Varying Aspect Ratios up to Thin Needles Achieving Free-Flowing Products
    Crystals 12 (2) (2022) 137

  • Claas Steenweg, Anne Cathrine Kufner, Jonas Habicht, Kerstin Wohlgemuth
    Towards Continuous Primary Manufacturing Processes - Particle Design through Combined Crystallization and Particle Isolation
    Processes (2021), 9, 2187

  • Claas Steenweg, Astrid Ina Seifert, Nils Böttger, Kerstin Wohlgemuth
    Process Intensification enabling Continuous Manufacturing Processes using Modular Continuous Vacuum Screw Filter
    Org. Process Res. Dev. (2021) 25, 11, 2525–2536

  • Claas Steenweg, Astrid Ina Seifert, Gerhard Schembecker, Kerstin Wohlgemuth
    Characterization of a Modular Continuous Vacuum Screw Filter for Small-Scale Solid-Liquid Separation of Suspensions
    Org. Process Res. Dev. (2021), 25, 4, 926–940

  • Claas Steenweg, Kerstin Wohlgemuth
    Von der Suspension zum getrockneten Produkt mittels neuartigem Vakuumschraubenfilter
    Filtrieren & Separieren 2021, 4, 4-11 
     

Patents

  • Claas Steenweg, Gerhard Schembecker, Kerstin Wohlgemuth
    Rotating-Screw Drying Reactor – Schneckenfördertrocknungsreaktor WO 2021/148108 A1

Oral presentations

  • C. Steenweg, J. Habicht, K. Wohlgemuth
    Continuous Particle Isolation by Solid-Liquid Separation, Washing, and Drying using the Small-Scale Continuous Vacuum Screw Filter
    3th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology (2021)

  • C. Steenweg, J. Habicht, G. Schembecker, K. Wohlgemuth
    Integrated Process Design of Continuous Solid-Liquid Separation, Washing, and Drying for Crystal Suspensions with Varying Crystal Shapes
    21st ISIC - International Symposium on Industrial Crystallization (2021)

  • C. Steenweg, A. Seifert, G. Schembecker, K. Wohlgemuth
    Characterization of a Continuous Small-Scale Solid-Liquid Separator for Filtration, Washing, and Drying of Pharmaceutical Suspensions
    12th PBP World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology (2021)

  • C. Steenweg, N. Böttger, A. Seifert, G. Schembecker, K. Wohlgemuth
    Holistic product quality control throughout the crystallization process chain focusing on continuous crystal isolation
    Jahrestreffen der ProcessNet-Fachgruppe Kristallisation (2021)

  • C. Steenweg, N. Böttger, G. Schembecker, K. Wohlgemuth
    Characterizing the Residence Time Distribution and Washing Zone within an Innovative Continuous Small-Scale Solid-Liquid Separator
    Jahrestreffen der ProcessNet-Fachgruppe Mechanische Flüssigkeitsabtrennung (2021)

  • Claas Steenweg, Gerhard Schembecker, Kerstin Wohlgemuth
    Crystal Product Design of Amino- and Dicarboxylic Acids
    CKB-Symposium, Düsseldorf (2019)